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Changzhou Jiayuan Chemical: Octafluoropropane Downstream Applications (Part 1)
time:2026-05-08 view:154

Fluorochemical Products R&D Center, Changzhou Jiayuan Chemical Co., Ltd.

Changzhou Jiayuan Chemical Co., Ltd. focuses on the field of fluorochemistry and has built a complete industrial chain from fluorite to high - purity hydrogen fluoride, electronic-grade hydrofluoric acid, trifluorochloroethylene, octafluorocyclobutane, inorganic fluoride salt series, boron-10 acid, electronic specialty gases, and downstream high-end fluorinated liquids (such as HFE449), truly achieving vertical integration throughout the AI big data market.

Changzhou Jiayuan Chemical Co., Ltd., relying on its self-controllable raw material advantages and large-scale production capabilities, can ensure stable product quality and reliable supply from source to finished product. The company's products are widely used in cutting-edge fields such as precision manufacturing cleaning, electronic heat dissipation and cooling, new energy, and semiconductor testing, and the company is committed to providing global customers with high-performance, low-environmental-impact fluorochemical solutions.

Changzhou Jiayuan Chemical Co., Ltd. will continue to focus on the fluorochemical industry chain, promote the technological iteration and industrialization of green fluorosolvents, and contribute to the sustainable development of the industry.




Octafluoropropane (C218/R218, chemical formula C₃F₈) is a colorless, non‑flammable, chemically stable perfluorinated compound. Its main applications are concentrated in three core industries: microelectronics, healthcare, and refrigeration. These applications are based on its chemical stability, non‑flammability, low toxicity, and specific physical properties (e.g., low boiling point, ultrasound contrast capability). The following sections provide a detailed description of its uses, end‑use industries, and the properties that enable them.

1. Microelectronics Industry – Core use in chip manufacturing

The microelectronics industry is the largest consumer of octafluoropropane (https://www.jy-chemical.com/octafluoropropane-product/), accounting for more than 60% of global consumption. The key properties exploited are its chemical stability, low reactivity, and excellent plasma etching performance.

1.1 Plasma etchant

Use: Fine etching of integrated circuits (ICs) and semiconductor chips (including 5nm and below process nodes), especially for patterning materials such as silicon, silicon dioxide (SiO₂), and silicon nitride (Si₃N₄).

Properties leveraged: High chemical inertness: in plasma state it reacts only with target materials (e.g., silicon) without corroding other chip structures, reducing process defects. The fluorine radicals (F·) generated during decomposition have moderate activity, providing controllable etch rates and enabling nanoscale precision for fine structures such as transistor gates and interconnect lines.

1.2 Device surface cleaning agent

Use: Removal of residual photoresist, metal contaminants (e.g., copper, aluminium), and polymer residues generated during chip manufacturing.

Properties leveraged: Insoluble in water but volatile, so no additional drying step is needed after cleaning, avoiding moisture‑induced oxidation damage to chips. Low toxicity and no reaction with chip materials (e.g., metal electrodes, insulating layers), thus no new impurities are introduced.

Application scenario: Precision cleaning processes in semiconductor assembly and testing (packaging). The most important medical use of octafluoropropane is as an intraocular gas tamponade after vitrectomy, mainly to assist retinal reattachment and promote macular hole healing. It utilises its chemical stability, good biocompatibility, and controllable absorption to create a stable environment for ocular tissue repair. A typical example is given below.

image 

2. Medical applications – Adjuvant treatment for rhegmatogenous retinal detachment (RRD)

Rhegmatogenous retinal detachment is a common ophthalmic emergency, where the neurosensory retina separates from the retinal pigment epithelium. Without timely treatment it can lead to blindness. Octafluoropropane plays a critical role as an “intraocular support” in such surgeries:

Treatment principle: After vitrectomy to remove haemorrhage and proliferative membranes from the vitreous cavity, octafluoropropane gas at a concentration of approximately 18‑20% is injected into the eye. The gas expands inside the eye and tamponades the retinal break (especially those located in the mid‑peripheral or inferior retina), pressing the retina back against the pigment epithelium. At the same time it blocks the flow of subretinal fluid, giving the edges of the break time for cell proliferation and adhesion repair.

Key advantages: Compared to air (intraocular residence time 1‑3 days), octafluoropropane has a longer absorption period (about 1‑2 weeks), providing longer‑lasting tamponade and reducing the risk of post‑operative redetachment. Its chemical stability means it does not react with ocular tissues (e.g., lens, iris), and the incidence of post‑operative complications (such as accelerated cataract progression) is lower than with other long‑acting gases (e.g., sulphur hexafluoride).

Clinical operational details: After surgery, patients must maintain a specific head position (e.g., face‑down if the break is located inferiorly) to ensure that the gas continues to tamponade the break. The gas is gradually absorbed over 1‑2 weeks; after retinal reattachment, no second surgery is required to remove it.

Continued in the next chapter


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