BASIC INFORMATION:

Product Name: 1‑Bromo‑3,5‑dichlorobenzene

Chemical Formula: C₆H₃BrCl₂

Synonym: 3,5Dichlorobromobenzene, 3,5Dichloro1bromobenzene

CAS: 19752-55-7

HS Code: 29039990

Molecular Weight: 225.90

Einecs: 243-270-7

Structural Formula:

Brief Description:

1Bromo3,5dichlorobenzene is a white to slightly yellow crystalline solid with high symmetry. It is widely used in the synthesis of dyes, pharmaceuticals, and pesticides.

TECHNICAL INDICATORS:

APPLICATIONS:

1. Pharmaceutical intermediate: Used in the synthesis of antifungal drugs (e.g., benzene ring analogues of miconazole and econazole) and antiparasitic agents. Example: Ullmann coupling to form a diaryl ether structure for enhanced antifungal activity.

2. Pesticide intermediate: Used to prepare diclosulam‑type herbicides and phenylpyrazole insecticides (e.g., chlorine analogues of fipronil).

3. Dye intermediate: Acts as the diazo component for azo dyes to produce bright yellow to red disperse dyes, such as certain Disperse Yellow series.

4. Flame retardant feedstock: Utilizes bromine‑chlorine synergy; can be used to synthesize bromine‑chlorine flame retardants, e.g., alternatives to tetrabromobisphenol A.

STORAGE CONDITIONS:

1. Store in a cool, dry, well‑ventilated area.

2. Keep container tightly closed; store in a cool, dry, ventilated place.

3. Separate from oxidizing agents and combustible materials – do not mix storage.

4. Ventilation systems should be equipped with static electricity grounding.

5. The storage area should be equipped with spill containment and appropriate collection materials.

PACKAGE:

1. Tightly sealed container.

2. Other packaging forms available upon request.

CHEMICAL PROPERTIES:

Melting point: 73–75°C, boiling point: 232°C (757 mmHg). Solid crystals, soluble in hot ethanol, toluene, and dichloromethane. The bromine atom is more reactive than the chlorine atoms, allowing selective palladium‑catalyzed coupling reactions. Dust is irritating; avoid inhalation during handling.