BASIC INFORMATION:

Product Name: 3,5-Dibromofluorobenzene

Chemical Formula: C₆H₃Br₂F

Synonym: 1,3-Dibromo-5-fluorobenzene

CAS: 1435-51-4

HS Code: 29039990

Molecular Weight: 253.89

Einecs: 215-860-4

Structural Formula:

Brief Description:

3,5-Dibromofluorobenzene is a pale yellow transparent liquid containing two symmetrically disposed bromine atoms and one fluorine atom. It is an ideal difunctional substrate for constructing disubstituted aromatic compounds.

TECHNICAL INDICATORS:

APPLICATIONS:

1. Pharmaceutical intermediate: Used in the synthesis of antitumor drugs (e.g., diarylurea analogues of sorafenib) and immunosuppressants (e.g., fluorine‑containing benzene rings of tacrolimus).

2. Pesticide intermediate: Used to prepare diamide insecticides (e.g., dibromo analogues of chlorantraniliprole) and imidazolinone herbicides (e.g., fluorine‑containing derivatives of imazamox).

3. Liquid crystal materials: 3,5-Dibromofluorobenzene serves as a bis‑reactive site for synthesizing rigid rod‑like molecules bearing two mesogenic units, used in wide‑temperature‑range liquid crystals.

4. Conjugated polymer monomer: Via Yamamoto polymerization or Suzuki polycondensation, used to synthesize fluorinated poly(p‑phenylene vinylene) (PPV) and other light‑emitting polymers for OLED emissive layers.

STORAGE CONDITIONS:

1. Store in a cool, dry, well‑ventilated area, protected from light, away from fire and heat sources.

2. Keep container tightly sealed; good sealing is required to prevent moisture absorption and volatilization. Glass or high‑density polyethylene containers are recommended; store in a well‑ventilated cabinet.

3. Storage temperature ≤30°C, relative humidity ≤80%; keep away from acids.

4. Ventilation systems should be equipped with static electricity grounding.

5. The storage area should be equipped with spill containment and appropriate collection materials.

PACKAGE:

1. Sealed glass bottles or HDPE bottles.

2. Other packaging forms available upon request.

CHEMICAL PROPERTIES:

Boiling point: 204206°C (768 mmHg), flash point: >110°C, refractive index: ca. 1.5770. Both bromine atoms can undergo halogenmetal exchange or coupling reactions; under the influence of the fluorine atom, the reactivity of the two bromines (positions 3 and 5) is similar. Density is high (2.018), so the material feels heavy when handled. Irritating to skin and eyes; avoid contact.